I wish the same for you! This involves using an X-ray image of the heart arteries and injecting a chemical called acetylcholine. it could be the vagus nerve, Ileocecal valve is linked to POTS and nerve function, Vagus nerve controls the function of the valve, Gastro motility linked to migrating motor complex (cleaning up digestive system), Triggered by signals from the vagus nerve, A kidney stone turned up 3 days after being cleared for kidney stones, The doctor confirmed the ileocecal valve was problematic, Two parts of vagus nerve: preganglionic (extremely long) and postganglionic (extremely short), Diana tried to stimulate the postganglionic nerve, The vagus nerve is a nicotinic acido cholinergic nerve (nicotine is the imitator of the vagal neurotransmitter), She put a nicotine patch over the side of the ileocecal valve, Within hours, the symptoms began to subside. Please take a look! :) Dr. D, Dr Driscoll and Ben…thank you so much for the valuable information. As you heard, this ended up not being just a vagus nerve problem, nor was it limited to a handful of vitamin deficiencies! At POTS Care, we see so, so many mood disorders (including depression and a bipolar-type presentation, but also a lot of high anxiety and OCD-type tendencies). Today, my podcast guest, Dr. Diana Driscoll, is the individual who actually designed that blend, and who knows a heckuva lot about the vagus nerve and its interplay with our bodies. It's still working for me. Many of us push through some symptoms, thinking we’re just stressed or working out too hard. Two things I would strongly suggest are Parasym Plus and NAC MAX. Dr. Diana Driscoll is an optometrist who had always been healthy – she was also a bit of an exercise fanatic and geeked out with nutrition. He gets a “tiredness” behind the eyes. Answers and Rationale. The Social Introvert. This leads to a temporary blockage, which may lead to a heart attack if the heart muscle is starved of oxygen. Parasym Plus should be sufficient to handle any issue with your vagus nerve or acetylcholine release. She has had a list of health concerns all her life. I’ve received a few emails about new podcasts but none of them are actually showing up. Order using my link and receive a nice bonus gift with your order! A Little-Known Secret To Fix Your Vagus Nerve, Banish Constipation, Use Nicotine As A Biohack & Much More! Thanks for the great question, YES! Thus, it appears unlikely that the alcohol-related suppression of REM sleep is mediated by alcohol’s effects on the acetylcholine system. I hope it is hugely helpful for you! In fact, my doctors wanted me to remove my gallbladder – my ejection fraction was a pitiful 8%. Hang in through that tough beginning when you start back! I have a serious, life-threatening allergy to soy and was alarmed that the company did not include this critical safety information on their website. Dr. Driscoll is considered to be “the patients researcher”, bypassing notoriously slow academic research institutions to get answers quickly. I’m so happy to hear that Parasym Plus is helping! Hi Randeep, You may be the rare bird who is just fine — someone I *really* envy!. "GREENFIELD" Seems to be working on my end. With regards to genetic expression and epigenetics – have you touched base with Dr. Dan Stickler of Aperion? (just mention Ben). If you have lupus, will you also consider controlling the oxidation that can contribute to damage? If you are dealing with IBS-C and your doctors have ruled out the usual causes, you can look at other signs/symptoms of autonomic dysfunction. Grades K-6 "Brain It!" I am mostly concerned with taking it in the morning at or around the same time as my Synthroid…. My Mom is 89. I got so bad that I couldn’t even answer the phone — it was too stressful! Is that okay? [Transcript] – Microdosing For Sports Performance, Microdosing Stacks With Psychedelics & Plant Medicines, The Best Microdosing Protocols & Much More With James Fadiman. Click here for the full written transcript of this podcast episode. I had 2 trauma’s to my head that required stitches, the 1st was when I was about 5 years old, the 2nd about 12 years old. The BHF note that the spasms occur when there is too many "tightening chemicals" and not enough "relaxing chemicals" in the body. Any issues with mental fatigue or brain fog, tendency to get constipation or dry eyes — that sort of thing. I kid you not. Reasons typical stimulants of the vagus nerve won't work: Some inflammatory cytokines block the release of acetylcholine. Interestingly, my mom developed POTS when she was 77! My mom developed POTS at the age of 77! you may choose to try that. All the Best! We have tested samples of alpha-GPC with a test to determine allergens called PCR (lab is Genetic ID), and we do not detect DNA fragmentation for soy at any level. I find heart rate variability to be helpful, but perhaps overly sensitive (people can raise it just by doing a math problem in their head, for example). At one point, my diarrhea got so bad that I was having around 35 “bowel movements” a day — Gads! Those are all clues! 1. As we get older, inflammation goes up naturally (what is called “inflammaging”). I’m curious if the medication I am to start also affects acetylcholine, I wonder if that is why this Dr said ‘the vagus LOVES gabapentin’. Seems when viral issues flair up he will complain of stomach pain, nausea and pain behind the eyes. Here is his book: https://www.amazon.com/Thiamine-Deficiency-Diseas…, Hi Kathleen, I absolutely developed Vitamin B1 deficiency — but I became deficient in most everything! Tiffany, if your vagus nerve is not having problems, the only thing you may notice with Parasym Plus is improved cognition. 4 months later and NO better than before because it felt like I added more symptoms to my body was getting shut down. Do you think Parasym+ can improve TBI sypmtoms? Parasym Plus will support the “rest and digest” system of the body (the parasympathetic nervous system) and NAC MAX will hit the oxidation that results from the chronic inflammation (this alters the brain chemistry toward anxiety). With diarrhea, you, of course, need to rule out the “regular stuff”. If your sister was my sister, I would suggest Parasym Plus AND NAC MAX — both of them. ... acetylcholine: a neurotransmitter ... Not too soon, not too late. It is so easy to get sufficient B vitamins! Express. I lost my short-term memory completely (and even got to the point that I couldn’t read). It can be inherited. I do not suffer from POTS, EDS, or MCAD and have read that buyers should be cautious when using this supplement for more general concerns alone like constipation, that aren’t accompanied by the specific diagnoses the product was created for. I have been for 8 months having issues that I just couldn’t pinpoint and understand. One thing you said, though, gives me pause — his nausea and pain behind his eyes. Sorry I’m a little late to the party but any issues taking this with non-hashimoto’s hypothyroid? I was diagnosed with Lupus and POTS in February, months before that I worked out and did strength training 4-5 times a week. For example, she’s been told no nsaids, no alcohol, etc. Are there any bad side effects from taking it if the vagus nerve is not having issues? If you have issues with inflammation for any reason, acetylcholine release is diminished. As a never-smoker…can I assume the lowest dose nicotine patch is enough, and I place it over the area and leave it on for the time recommended on the box? We have seen what other doctors have called “the worst case of dry eyes I’ve ever seen” reverse completely. You can unsubscribe at any time. When I looked back on my life and that of my kids I could see signs — and wish I knew then what I know now so we could have avoided becoming so sick! Causes. I thought this was a fascinating and important episode, and was intrigued enough by it to order the Parasym Plus. Sometimes they'll include recommendations for other related newsletters or services we offer. The brain uses acetylcholine for short-term memory, for sharp cognition, and for “executive function” (the ability to juggle many things at once and still stay organized). :) Dr. D, I get it, Biff! Inflammatory cytokine release in exercise is a U-curve, if you will (the higher inflammation being at the tops of the U). Really enjoyed the episode and much props to Dr. Driscoll for not giving up here. Unlike angina caused by fatty deposits of cholesterol, variant angina occurs when a spasm occurs in the muscle layer of the arterial wall. The trick is that you still need some functional gland! Her peer-reviewed medical abstracts include those involving vascular abnormalities in the fundus of POTS patients, the etiology of left ventricular diastolic dysfunction, and the use of acetazolamide in multiple sclerosis. Imagine feeling like you have sand in your eye all of the time. With opioids, for example, constipation results. The under-diagnosed condition causes chest pain caused by tightening of a heart artery. However, due to the current FDA Food Allergen Labeling & Consumer Protection Act (FALCPA) ruling, alpha-GPC currently requires the labeling of ‘soy’. (And don’t forget the “Greenfield” coupon! These medicines prevent an enzyme from breaking down a substance called acetylcholine in the brain, which helps nerve cells communicate with each other. I think my wife is struggling with some of the things gone over here. My mom has been taking parasym + since we got it, (about 2 1/2 weeks ago). Her dry eyes have maybe gotten worse but we know she hasn’t been taking it long enough yet for that benefit. Ordered the Parasym and wishing the positive best to reboost my system. If someone struggles (like I do) with some chronic inflammation PRIOR TO THE INJURY, they do much worse. Hi Stephanie, If Sjogren’s is in its early stages (that is, the lacrimal gland is not completely destroyed), then Parasym Plus will provide the lacrimal nerve the stimulus needed for the lacrimal gland to produce more tears. I hear Ben say a lot of negative things about soy and soy products but have never heard why he steers clear of it. Do you feel this is safe for my wife to take while still pumping for my daughter? If you wanted to do more, I would be tempted to dig deeper into your case. Rich sources of magnesium include spinach, nuts, seeds and legumes, but habitually eating low intakes of such foods may lead to a deficiency. ): https://vagusnervesupport.com/athletes-vagus-nerve/ The NIH identified groups of people who are at higher risk of a magnesium deficiency which includes those who have: "Habitually low intakes of magnesium induce changes in biochemical pathways that can increase the risk of illness over time," said NIH. ;) A propensity for Vitamin B1 deficiency has already been published concerning POTS (as has Vitamin B12 deficiency). It is designed to deliver the medicine continuously, a little at a time, to improve absorption and reduce off-times. Thank you for the support, Hans! Hi Ben, I listen to your podcasts using the podcasts app on my iPhone but your episodes aren’t updating. Some days are better than others, so I’ve decided after almost 6 months I would try going back to the gym. I came up with some special Digestive Enzymes and Soothing Digestive Aid for those who needed some additional support for a while (or for those who weren’t lucky enough to safe their gallbladders). But he still takes Parasym Plus every day for the cognition. Of course, he was actually Patient One — I was Patient Zero (lol), but his lack of nutrient absorption, leading to severe osteoporosis when he was about your son’s age was one of my biggest motivators to getting answers! The severe constipation could be from many things (opioids for pain, some antibiotics, etc), BUT because low acetylcholine release is common as we age (called “inflammaging”) and because inflammation occurs with trauma (physical trauma to the body includes damage from ulcers), Parasym Plus could absolutely help her. Fingers crossed!! All best wishes, Teja, Your email address will not be published. Ultimately, she was diagnosed with something called POTS (Postural Orthostatic Tachycardia Syndrome) – a disorder of the autonomic nervous system and was told there was no cure for this mysterious condition. So it really is trial and error. Does this affect you? HI Ben, thank you for your fabulous podcasts and amazing body of work. That probably counts as TBI I suspect. My mom has suffered from exactly the same symptoms. The lower esophageal sphincter, located between the esophagus and the stomach, … Brain support + vagus nerve + lacrimal nerve (tear production) — nothing else does it all. Her work in chronic inflammation, the autonomic nervous system, collagen disorders, and organ dysfunction can help others live their best life, as well as have their best body and mind. If you are interested in this, you can call POTS Care and ask for a free copy of “The Driscoll Theory” where this was first released. Even with an on-off split, curious about the effects of long term acetylcholinesterase inhibition. My guess is you saw some major starbursts and glare at night time — does that sound familiar? I’m curious to know if you figured out your dizziness? Your email address will not be published. If we get super sick (as your mom and I did) it DOES become more important to us, but I see SO MANY people who think they just need to deal with some things because they are getting old, or are stressed out, or are working (or working out) too hard. Thank you guys so much for what you do. Hi Rebecca, It sounds like you were hitting the gym pretty hard before you got sick! I’m pulling for you! My diagnosed IBS-C has responded relatively well to a prokinetic agent (prucalopride) for 2 months now, but as well as not being able to remain on it long term it’s still not a perfect fix and requires a host of other actions on my part to keep things moving. If you are trying to figure this out you can also look for other signs of vagus nerve problems (or like you heard, acetylcholine problems). These two are a powerful combination. I was so flooded with norepinephrine (think “adrenaline”) that not only was I unable to fall asleep (sometimes for days), my anxiety and fear went nuts! This was a neurotransmitter problem, which means it can affect other areas of the body that depend upon the same neurotransmitter (acetylcholine). Interestingly enough I seem to have similar issues too with that eye strain and digestive distress. Any experiences with this? I join you in your quest to be proactive in your health, Ron! :). Hi Ben, Dr. Diana, I was mesmerized by this podcast. 2/13-2/19. She recovered, thank God but since has suffered from severe constipation. I usually start off fine but about halfway through my meal the food will get to the back of my mouth and it feels like everything freezes up and the normal automatic swallow process doesn’t happen and I have to really concentrate to get the swallow to initiate. Your favorite organic food and products. What would you recommend for me as I begin my journey back to the gym? Everyone is different, but perhaps what we learned (and what was missed by our doctors) could be helpful for you? Those products (and why they are special) are on the same website. Now I am very appreciative of the POTS diagnoses and educational discussions about the connection with Vagal and ILEOCECAL relationships that I didn’t find on my many oh so many insomnia nights of looking up information on line. When I got a new phone, placed my old SIM card in it and opened Castbox, there was all the podcasts and it updates now. My husband has never been sick with vagus nerve issues, but he began to lose his memory — we were both terrified! In addition, severe magnesium deficiency can result in personality changes, abnormal heart rhythms and coronary spasms. We just had a patient at POTS Care whose dad is a physician and he said she had chronic constipation from her opioids. is a card game similar to "Go Fish." It’s part of the right-brained nervous system regulation work of SRT (Self Regulation Therapy) as developed by the Canadian Foundation for Trauma Research and Education and gives health practiioners a ton of insight into vagal tone and how to use it to guide diagnosis, prognosis, and therapy progress among other things. I guess. A few months ago, I briefly mentioned on a podcast that I discovered that by taking a specific blend of nutrients to support my vagus nerve, I was able to completely get rid of morning constipation. –Parasym Plus (use code GREENFIELD for 10% off on all products! 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